What Are the Side Effects of Zepbound Injection for Weight Loss?

zepbound side effects

Zepbound is a prescribed injectable medication. It helps you to treat your sleep apnea and weight gain-related issues. This drug is prescribed mostly to adults and should be taken after the doctor’s advice. You must know that most medications, whether injectable or not, have possible side effects. As per the reports, people after consuming Zepbound have diarrhoea, vomiting, or nausea. This might affect your overall health. You need to know in detail about the possible side effects after using Zepbound. And what are the recommended solutions to reduce the side effects? Go through the blog to find out all the answers to your queries.

What are the very common side effects of using Zepbound?

Zepbound can have some visible side effects on your body.  It affects your health and can be fatal sometimes. You might get a few common health issues, which include cases that last for a long time and are very dangerous. In case these symptoms worsen, you need to consult a doctor. Don’t ignore them, as there are possibilities of getting serious health issues.

You might get the following health effects on your body after consuming Zepbound:

  • Vomiting
  • Diarrhea
  • Constipation
  • Pain in the abdominal area
  • Digestion-related issues
  • Reaction in the skin where the injection was given.

To know in detail about the side effects and solutions, don’t stop here; go through the blog.

Listing some low-impact side effects of Zepbound

You might experience a few low-impact or mild symptoms after using Zepbound. Although it’s not possible to figure out every mild side effect, the most common ones are mentioned below. To get information about Zepbound, you can follow the blog in detail.

  • Digestion-related issues
  • Constipation
  • Normal to severe vomiting
  • Frequent Nausea
  • Pain in the abdominal region
  • Irritation or redness in the skin after an injection
  • Allergies
  • Loss of hair
  • Blood pressure-related issues
  • GERD or gastroesophageal reflux disease

These are a few common low-impact side effects of using Zepbound. You can get these possible health issues. The symptoms generally have a mild impact on your health for a short time. But in case any of these symptoms last more than a week, then immediately consult your health expert. It is a sign that Zepbound doesn’t suit your body, and you need to take immediate action.

Have a look – The Food Administration has approved the use of Zepbound for treatment. So, it is safe for general use. But few patients have reported that side effects of Zepbound, including mild and serious symptoms, have been found. When clinical trials were conducted, few side effects were listed by the organisation.

In case you are using Zepbound regularly, then along with mild symptoms, you must also know about the severe side effects associated with the use of Zepbound.

Severe Side effects of using Zepbound

Zepbound may cause serious side effects. When the scientific study was made, no such severe side effects were found. But gradually, after its application on humans, reports of some mild to severe health issues have come to light. In case you are planning to use Zepbound, then go through all the information given on the site.

There can be some harmful side effects due to the use of Zepbound on your body. When the clinical trials were conducted, these side effects couldn’t be detected well. We don’t claim that the list mentioned below covers all the severe side effects associated with Zepbound use. But you can find the most likely severe side effects in the list.

  • Serious Digestion-related Side Effects – You may get constipation for more than a week. It may be associated with Vomiting and nausea, lasting for a long time, which can make you feel extremely weak.
  • Critical Kidney disorder – Zepbound use might affect your kidney, and possible signs include hand, nausea, and foot swelling along with cramps in muscles or vomiting.
  • Serious gallbladder-related diseases, like cholecystitis. It involves stone formation in the gallbladder along with inflammation. Possible symptoms associated with this are: Jaundice, pain in the abdominal area, and fever.
  • Pancreatitis – Your pancreas can become inflammation, which is a matter of serious concern. Pain in the back and abdominal region is a possible sign of getting Pancreatitis.
  • Severe allergies might occur in case Zepbound doesn’t suit your body.
  • Blood pressure is impacted. You might get low blood pressure as a side effect.
  • You may be prone to getting thyroid problems.
  • The development of thoughts related to suicide can increase. You may face depression and anxiety or lose interest in everyday activities. You might have mood swings or feel hopeless about life. Although these side effects were not found during clinical trials, people who have used Zepbound have reported depression and anxiety issues.

However, the FDA has a strict warning for patients with thyroid conditions to use it very consciously.  Their risk is higher, and Zepbound might have fatal health concerns.

What are the specific side effects associated with Zepbound use?

If you want to know the specifics of the side effects of using Zepbound, then go through it carefully.  During clinical trials, some of the side effects have been found.

  • Increased risk of Thyroid Cancer

You can get a box warning in Zepbound injection packs. These are the strict warnings and shouldn’t be ignored at all.  These box warnings are the high alerts for the patients and healthcare experts, which must be taken care of while taking the medications.

When tested on animals, Zepbound has resulted in thyroid tumours. So it can be predicted that humans might also get thyroid tumours. It is not certain that humans will definitely get thyroid tumours.

You might get thyroid cancer after using Zepbound. Symptoms like difficulty breathing and difficulty swallowing are common. You might also get your neck swollen or a lump on it.

What measures need to be taken?

Family medical history diagnosed with MTC or MEN2.

Do you have any family medical history associated with medullary thyroid carcinoma MTC?  If your answer is yes, you must avoid using Zepbound.  In case your family members have multiple endocrine neoplasia syndrome type 2 MEN2, you must not use Zepbound. The risk of getting harmful side effects is much higher in such cases than in people without a medical history. Reach your doctor and get some other options to lose weight or treatment for sleep apnea.

In multiple endocrine neoplasia syndrome type 2 MEN2, a few tests will be taken.  After a proper diagnosis is made, you might be recommended by the doctor to reduce or stop the use of Zepbound. So, do not ignore the harmful effects and reach the doctor immediately. With these health risks, other methods of weight loss are generally recommended.

Reaction at the site of injection

After taking Zepbound, you might get a reaction in the skin where it was injected. As Zepbound is an injectable medication, you might face a little problem. Generally, Zepbound creates irritation in the area where the injection is given. When scientific clinical trials were conducted, this was the most common side effect found by them.  You may get the following symptoms due to the injection –

  • Rashes on your skin
  • Pain in the area where Zepbound is injected
  • Itching and sensation
  • Redness in the skin

In case you find such issues, what steps do you need to take now?

  • Commonly, the sudden effects of the injection of any medication go away after a few hours or days automatically.
  • In case the effects do not vanish on their own within a short period, then you need to take some steps. Consult a doctor; you may be advised to take Tylenol to reduce the pain caused by the injection. For rashes and itching, you may be advised to use Benadryl.

Digestion-related issues

After using Zepbound, a few side effects related to digestion were found. These might be mild in a few cases, and may turn into extremely harmful in others.

  • The issues like constipation, gastric problems, or vomiting are common digestive side effects. You might also face indigestion, GERD, or nausea.
  • Other than these common and mild effects, some very harmful digestive issues like acute gallstones and severe pancreatitis are also reported.

Apart from the effects mentioned here, you should ask the pharmacist and doctor for other possible side effects.

What to do next?

In case you are facing low-impact side effects like vomiting, constipation, or indigestion, then prefer taking some remedies available at home.

But for harmful and serious side effects like gastroparesis, you must rush to the doctor. Ask them to provide some alternative solutions for weight loss and sleep apnea in place of Zepbound.

Allergy to Zepbound

Zepbound might result in giving you allergies in many places. When trials were made, the side effects related to allergic reactions were less.

Some of the allergies associated with Zepbound use are –

  • Rashes on the skin
  • itching in different body parts
  • Swollen under eyes, skin, feet, or hands
  • Tongue or throat swelling
  • Breathing difficulties.

In case you find such allergies, then go to the doctor immediately. Do not ignore them as the mild one can turn into severe. They will guide you on whether to take Zepbound, reduce the dose or completely stop using it. They might recommend certain anti-allergy pills, too. In case you get serious health deterioration due to an allergic reaction, then call the emergency helpline and reach the hospital as soon as possible .

What are the Precautions for Zepbound?

To take necessary precautions before using Zepbound, give clear information about your health conditions to your doctor. This will help him to give you proper precautions. You must inform them about your health conditions, diseases, and the medicines you take.

Box Warning in Zepbound

Zepbound comes with a boxed warning for all its users. This warning includes thyroid tumour risk by using Zepbound. A serious warning is issued by the health organization and must be followed.

Advisory precautions are :

  • In case you have Pancreatitis or any problem in your pancreas then inform the doctor . Zepbound can affect your pancreas and lead to some disorders . Inflammation and swelling in pancreas can be caused due to Zepbound.
  • Kidney related issues must be addressed too. Discuss with your doctor about it. Zepbound might worsen your kidney disease and can lead to kidney dysfunction. Clarify whether you can use Zepbound or not in such conditions.
  • Serious Digestion related issues like gastroparesis, indigestion, or severe vomiting and nausea must be addressed. By using Zepbound for prolonged periods such Health issues might worsen. So, ask whether you can use it or not with digestive issues.
  • In case you have diabetes or a low sugar level, discuss with your doctor before starting the treatment. Zepbound is known to reduce the level of your blood sugar. So, diabetes patients can face difficulties after using Zepbound. In case your diabetes doctors recommend that you follow a certain dose of Zepbound. This will help in reducing the effects of getting a low sugar level. But if the sugar level reduces continuously, then you are not advised to use Zepbound. Other available medications for treating sleep apnea or weight gain can be used.
  • Zepbound can lead to pulmonary disease. In case you have surgeries to be done in future, inform your doctor before starting the use of Zepbound. In case you want to continue with Zepbound during your surgery period then special doctor recommendation is required.
  • Those facing allergies due to Zepbound use , must be due to the composition of the medication. You need to consult with your doctor for some alternative options available. Allergic reactions can turn into serious health issues and can create a lot of damage. So do not ignore the impacts and rush to the doctor.
  • In case you are pregnant and breastfeeding your baby, then do not ever take Zepbound. It is completely unsafe to take Zepbound during such periods. No trials have found Zepbound to be safe during pregnancy or breastfeeding, so avoid using it. In case you lose weight during your pregnancy, it can impact your fetus’s development. You may ask your doctor to advise on some other medications for sleep apnea.
  • In case you are taking birth control pills, do not take Zepbound a few times during this period. It can reduce the effects of birth control pills. You invite an unwanted pregnancy. Consult with your doctor to advise you on the birth control pills that are not impacted by Zepbound and work effectively.
  • In case you are taking excessive alcohol, Zepbound is not advised for you. Your health care expert might advise you on the appropriate amount of alcohol to consume while taking Zepbound. Try avoiding the use of alcohol during the treatment.

Zepbound is a well-known medication used for treating sleep apnea and weight gain. But it involves certain side effects. These may have low impact or severe impacts. Do not ignore them and reach your doctor. They will help you answer all your queries related to side effects, precautions, and alternative solutions to Zepbound. Ignoring the side effects might invite some serious health disorders. Always buy Zepbound from authorised stores and read the boxed warning. It contains a lot of information that you st know about your case if you want to start your treatment using Zepbound.

2025-05-26