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When do Antidepressants Start to Work?

When do Antidepressants Start to Work

Among the most common mental illnesses in our society is depression. This condition affects many people around the world, and today, the most effective and usual treatment is the use of antidepressants. However, not everyone is convinced by this method, nor are all patients given results, so it is always important to consult a doctor before starting medication.

One of the main doubts among people suffering from depression is about when antidepressants begin to take effect. Unlike other immediate action drugs, antidepressants offer longer-term results. In this article we tell you everything in more detail.

When will I notice the effect of antidepressants?

When our head hurts, we take a pill and in a matter of ten minutes we already feel improvement. But when we talk about an ailment that affects mental health, as is the case with depression, its action is not immediate, and you must be patient with treatment.

Taking antidepressants is the most common method prescribed by doctors when a person is living a stage of depression or anxiety. These drugs significantly improve the patient’s quality of life, although the effect will begin to be noticed over the days. The reason is that antidepressants are medicines that help to rebuild brain neurotransmitters, and, therefore, this process is slower and more complex than a simple headache.

So, when do antidepressants start to take effect? It usually takes an average of two weeks for patients to begin to notice results. The vast majority start to feel better from the second week, but it’s not until the third or fourth when they can feel better.

Therefore, you must have this timing in mind so that you do not lose patience and continue to take care of yourself. A doctor must follow up on your health and prescribe the most suitable type of antidepressant for your body and condition. In these cases, patience will be your best ally because antidepressants work and will help you feel better, but you have to know that the effect takes time to arrive, and, on the other hand, the side effects may be more immediate (e.g., headache, dry mouth, etc.).

Antidepressants can cause side effects on your health, but most are mild and still have simple discomfort. In the case where you feel these effects are too powerful or annoying, talk to your doctor to regulate your medication or change your antidepressant. One point you should also keep in mind is that, more than likely, you will try different antidepressant typologies until you find yours.

Tips if you’re taking antidepressants

Now that you know that the effects of antidepressants usually take 2 weeks to appear, we’re going to finish this article by giving you some final tips to make your treatment more comfortable and less stressful for you:

Be patient. You mustn’t despair and know that, in the end, treatment will work for you. But at first, it can be a little complicated because you won’t feel the immediate effect, and besides, you may change your medications.

Do your part. In order to overcome depression, your attitude is vital. Therefore, if you are taking antidepressants and you have a good attitude, with energy and positivity, the effects will be faster and more noticeable.

Ask your surroundings for help. Finally, it’s important for your loved ones to know your situation, so ask for help and don’t be ashamed of it.


This information does not in any case replace the diagnosis or prescription by a doctor. It is important to go to a specialist when symptoms occur in case of illness, and never self-medicate.

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